The GLOBE program started its operation in Kenya in 1997 after the signing of the bilateral agreement between the United States Government and the Kenya Government but remained dormant since 2000. In 2007, efforts have been made to revive GLOBE activities due to the immense benefits its offers to students, teachers, and scientists as well as the host country in inculcating inquiry-based learning in teaching and learning.

In the Financial Year 2012/2013, the Kenya National Space Secretariat (KNSS), which was a precursor to the Kenya Space Agency, adopted the GLOBE program to be an outreach program to promote and sustain interest in the Science, Technology, Engineering and Mathematics (STEM) subjects, which are foundational subjects for careers in Space Science and Technology. Subsequently, upon establishment of the Kenya Space Agency in 2017, KSA took over the mandate of implementation of the GLOBE Program in Kenya.

A number of activities have been undertaken by KNSS and its successor KSA in the implementation of the GLOBE Program in Kenya. Some of these activities include;